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Custom DNA oligos

IDT’s long-standing reputation as a pioneer and leader in custom oligo manufacturing is primarily due to our proprietary synthesis platforms. Most components in our manufacturing process are designed and developed in-house, including specialized synthesizers that accommodate the most demanding oligo requests and high-throughput automation systems that ensure fast turnaround times. We do not rely on third-party manufacturers for the machines and chemical reagents used for synthesis, allowing us to easily refine equipment and reagents as necessary. Our ability to control these variables allows us to produce oligos that are unmatched in quality and consistency for use in routine and specialized applications.

DNA oligos »

Single-stranded, pooled, or duplexed DNA, synthesized to your specifications. Import multiple sequences from an Excel or text file or enter them individually using our convenient online tools.

Affinity Plus DNA & RNA Oligonucleotides »

Affinity Plus DNA & RNA Oligonucleotides and Affinity Plus Ultramer DNA Oligonucleotides are custom, single-stranded and duplexed sequences that contain locked nucleic acid (LNA) bases.

Alt-R HDR Donor Oligos »

Single-stranded DNA oligos specifically built for your homology-directed repair (HDR) experiments. Designed and optimized through extensive wet-bench testing, they are ideal for introducing point mutations and short insertions.

Ultramer DNA Oligos »

Long, high-quality DNA oligos up 200 bases. Manufactured using proprietary methods that result in more full-length product.

oPools DNA Oligo Pools »

Oligo pools are individually synthesized single-stranded DNA sequences that range from 40 to 350 bases. Each pool can be designed with up to 20,000 oligos in a single tube.

TruGrade DNA Oligos »

DNA oligos up to 120 bases manufactured by an exclusive production process to minimize oligonucleotide crosstalk. Useful for reducing the risk of barcode misalignment during multiplexed NGS applications.

Megamer Single-Stranded Gene Fragments »

Single-stranded genomic blocks up to 2000 bases. Synthesized from clonally purified DNA and sequence-verified via next generation sequencing.