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Limit off-target editing with CRISPR GUARD

CRISPR Guard Webinar

Precise genome editing using CRISPR-Cas9 is a promising avenue for genetic disease research. However, off-target editing effects can complicate and slow research.

In this webinar, Dr. Matthew Coelho discusses findings recently published in Nature Communications, “CRISPR GUARD protects off-target sites from Cas9 nuclease activity using short guide RNAs.”

In this webinar, he will:

  • Discuss the utility of CRISPR Guide RNA Assisted Reduction of Damage (CRISPR GUARD) as a method for protecting off-target sites by co-delivery of short guide RNAs (sgRNAs) directed against off-target loci by competition with the on-target guide RNA.
  • Explore design rules and the universality of this CRISPR GUARD method through in vitro studies and high-throughput screening
  • Short benefit statement for why one would want to attend the event; <50 words; include as many SEO keywords as possible, without stuffing

For research use only. Not for use in diagnostic procedures. Unless otherwise agreed to in writing, IDT does not intend these products to be used in clinical applications and does not warrant their fitness or suitability for any clinical diagnostic use. Purchaser is solely responsible for all decisions regarding the use of these products and any associated regulatory or legal obligations.

Event information


May 19, 2022


Central Standard Time