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Frequently asked questions
Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.
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What is the sodium salt exchange that is done after HPLC purification?
The sodium salt exchange we perform post-HPLC purification is a sodium acetate precipitation. It helps remove any remaining TEAA in the oligo preparation after HPLC purification.
It is important to make sure oligos used in in vivo assays are TEAA-free because it can be toxic to cells.