Your product is now available from Integrated DNA Technologies.
Many of the Swift products you have grown to love are now part of our new complete portfolio, xGen™ NGS. Through this new partnership we are pleased to offer you comprehensive next generation sequencing solutions.
xGen NGS—made for you.
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Frequently asked questions
Our Scientific Applications Support team has assembled a list of frequently asked questions to help you find answers quickly. Filter using one or more categories to focus on specific topics, or use the search bar to perform a text search.
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Is the xGen™ Methyl-Seq DNA Library Prep Kit compatible with reduced representation bisulfite sequencing (RRBS)?
The chemistry of xGen Methylation Sequencing easily works in an RRBS workflow. To capture the fraction of DNA fragments that are enriched for CpG islands, this RRBS protocol requires that size selection of inserts occurs after MspI DNA digestion, but before bisulfite conversion.
As the xGen Methyl-Seq DNA Library Prep Kit requires bisulfite conversion prior to library preparation, size selection must be performed on the DNA fragments immediately following MspI digestion (rather than on library molecules, as in the traditional workflow).